Basic life processes start in the cell. To understand how they function and respond to disease or genetic variations, life scientists engage in cellular and structural biology research. Cellular biology explores individual cells and the ways in which they are organized into organs and tissues. Structural biologists delve deep into sub-cellular components, organelles and macromolecular structures. Electron microscopy (EM) is capable of providing insight at all these scales and more, revealing even atomic-level structural details for a range of biomolecules.